Illumina
ILMN
$170.93
+5.16%
Illumina Inc. is a global leader in life sciences, providing tools and services to analyze genetic material for research and clinical applications, operating within the Medical - Diagnostics & Research industry. The company is the dominant market leader in DNA sequencing technology, generating over 90% of its revenue from sequencing instruments, consumables, and related services, which establishes it as the foundational platform for genomic research and clinical diagnostics. The current investor narrative is focused on the company's recovery and growth trajectory following a period of significant challenges, including the costly and ultimately divested acquisition of GRAIL, with recent attention on margin expansion, a return to solid profitability, and the execution of its core sequencing strategy amidst a competitive landscape.…
ILMN
Illumina
$170.93
ILMN 12-Month Price Forecast
Wall Street consensus
Most Wall Street analysts maintain a constructive view on Illumina's 12-month outlook, with a consensus price target around $222.21 and implied upside of +30.0% versus the current price.
Average Target
$222.21
10 analysts
Implied Upside
+30.0%
vs. current price
Analyst Count
10
covering this stock
Price Range
$137 - $222
Analyst target range
Analyst coverage for Illumina is limited, with only 7 analysts providing estimates, indicating it may have reduced institutional coverage following its recent challenges. The available data shows consensus estimates for EPS and revenue but does not provide a clear consensus price target, Buy/Hold/Sell distribution, or target price range. The estimated EPS for the period averages $8.83, with a narrow range from $8.72 to $8.95, suggesting analysts have high conviction on near-term profitability. The revenue estimate average is $5.83 billion. The lack of explicit price targets and the low analyst count typically implies higher uncertainty and less efficient price discovery, which can contribute to the stock's elevated volatility (beta of 1.424). Investors should seek out more recent and comprehensive analyst reports for a clearer view on price expectations and sentiment.
ILMN Technical Analysis
The stock is in a powerful, sustained uptrend, evidenced by a 93.36% gain over the past year. As of the latest close at $162.96, the price is trading at approximately 98.5% of its 52-week high of $165.37, indicating it is testing major resistance at the peak of its annual range. This positioning near all-time highs reflects strong bullish momentum but also suggests the stock is extended and vulnerable to a pullback or consolidation if it fails to break through resistance. Recent momentum has been exceptionally strong, with the stock surging 35.38% over the past month and 21.20% over the past three months, significantly outpacing the broader market's gains of 6.31% and 10.28%, respectively, over the same periods. This acceleration from the longer-term trend suggests a powerful, potentially news-driven rally, though the extreme short-term move raises the risk of a near-term correction. Key technical levels are clear, with immediate resistance at the 52-week high of $165.37 and support at the 52-week low of $78.79. A decisive breakout above $165.37 would signal a continuation of the bull trend into new high territory, while a failure could lead to a retracement toward the $150 level. The stock's beta of 1.424 confirms it is approximately 42% more volatile than the S&P 500, which is critical for risk management as it implies larger swings both up and down.
Beta
1.42
1.42x market volatility
Max Drawdown
-25.7%
Largest decline past year
52-Week Range
$82-$172
Price range past year
Annual Return
+108.9%
Cumulative gain past year
| Period | ILMN Return | S&P 500 |
|---|---|---|
| 1m | +22.6% | +5.0% |
| 3m | +33.3% | +10.7% |
| 6m | +32.5% | +10.0% |
| 1y | +108.9% | +26.5% |
| ytd | +27.2% | +10.6% |
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ILMN Fundamental Analysis
Revenue growth has stabilized and turned positive, with Q4 2025 revenue of $1.159 billion representing a 4.98% year-over-year increase. This marks a significant recovery from the volatile performance seen in prior quarters, including a major loss in Q2 2024, and indicates the core business is on a healthier trajectory. The sequencing segment, generating $1.065 billion in the latest period, is the unequivocal growth driver, while the microarray business contributed a smaller $94 million. The company has returned to robust profitability, posting net income of $334 million in Q4 2025 with a net margin of 28.8%. Gross margins remain strong at 67.04% for the quarter, consistent with the trailing twelve-month gross margin of 66.69%, demonstrating the company's pricing power and operational efficiency in its core business. This profitability recovery is a stark contrast to the deep losses incurred in mid-2024. The balance sheet and cash flow position are solid, with a current ratio of 2.08 indicating good short-term liquidity and a debt-to-equity ratio of 0.94 reflecting a manageable level of leverage. Most importantly, the company is generating substantial free cash flow, with TTM free cash flow of $939 million, providing ample internal funding for operations, growth investments, and potential shareholder returns, as evidenced by ongoing stock repurchase activity.
Quarterly Revenue
$1.2B
2025-12
Revenue YoY Growth
+0.04%
YoY Comparison
Gross Margin
+0.67%
Latest Quarter
Free Cash Flow
$939000000.0B
Last 12 Months
Revenue & Net Income Trends (2 Years)
Revenue Breakdown
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Valuation Analysis: Is ILMN Overvalued?
Given the company's positive net income, the primary valuation metric is the P/E ratio. The trailing P/E stands at 24.52x, while the forward P/E is slightly higher at 27.48x. The modest premium of the forward multiple suggests the market anticipates stable, but not dramatically accelerating, earnings growth in the near term. Compared to sector averages, Illumina's valuation appears elevated. Its trailing P/E of 24.52x and Price/Sales ratio of 4.81x are above typical levels for mature healthcare equipment companies, commanding a premium justified by its market-leading position in the high-growth genomics space and its return to profitability. Historically, the stock's current trailing P/E of 24.52x sits well below its own extreme historical highs seen in 2021 (over 90x) but is above the levels seen during its recent period of operational distress in 2023 and early 2024. This suggests the market has repriced the stock to reflect its recovered fundamentals, but is not yet pricing in the hyper-growth expectations of its past, positioning it in a more reasonable, mid-range historical valuation zone.
PE
24.5x
Latest Quarter
vs. Historical
Low-End
5-Year PE Range -56x~2943x
vs. Industry Avg
N/A
Industry PE ~N/A*
EV/EBITDA
19.4x
Enterprise Value Multiple

