Tempus AI
TEM
$50.02
-2.11%
Tempus AI operates in the healthcare information services industry, focusing on building a technology platform that liberates and structures clinical and molecular data for use in precision medicine. The company is a prominent disruptor in the oncology and diagnostics space, leveraging artificial intelligence, including generative AI, to enhance the accuracy and personalization of laboratory tests. The current investor narrative centers on the company's rapid revenue growth trajectory post-IPO and its path to profitability, as it aims to scale its data platform and AI-driven diagnostic tools in a capital-intensive, high-growth phase, with recent financials showing significant top-line expansion alongside persistent net losses.…
TEM
Tempus AI
$50.02
TEM 12-Month Price Forecast
Wall Street consensus
Most Wall Street analysts maintain a constructive view on Tempus AI's 12-month outlook, with a consensus price target around $65.03 and implied upside of +30.0% versus the current price.
Average Target
$65.03
4 analysts
Implied Upside
+30.0%
vs. current price
Analyst Count
4
covering this stock
Price Range
$40 - $65
Analyst target range
Only four analysts provide coverage for Tempus AI, indicating it is a relatively new and niche stock with limited institutional research. The consensus sentiment is bullish, with recent ratings from Guggenheim, Needham, HC Wainwright, and Morgan Stanley all being 'Buy' or 'Overweight', while JP Morgan maintains a 'Neutral' stance. The average revenue estimate for the next period is approximately $3.16 billion, with a wide EPS estimate range from $2.77 to $3.03, implying significant uncertainty around future profitability.
The target price range is not provided in the data, but the concentration of 'Buy' ratings from the few covering firms suggests analyst optimism about the company's long-term platform potential. The low number of analysts (4) and the recent IPO status typically correlate with higher stock price volatility and less efficient price discovery, as the investment story is still being established. The recent reaffirmations of Buy ratings in March 2026, despite the stock's steep decline, indicate maintained conviction among its core proponents, viewing the pullback as a buying opportunity for the long-term AI-in-healthcare thesis.
Bulls vs Bears: TEM Investment Factors
The bull case is anchored in Tempus AI's undeniable top-line momentum (83% YoY growth) and transformative gross margin expansion to nearly 90%, which signal a powerful business model shift. However, the bear case presents severe and immediate financial risks, primarily the massive -$404M annual cash burn that threatens the company's runway without further dilution. Currently, the bearish evidence holds stronger sway, as the market has rightfully punished the stock for its lack of profitability and unsustainable cash consumption, compressing its PS multiple from 51.8x to 8.1x. The single most important tension in the investment debate is the race between scaling revenue/margins and the cash burn clock: can the company achieve operating cash flow breakeven before needing to raise costly capital?
Bullish
- Explosive 83% YoY Revenue Growth: Q4 2025 revenue reached $367.2 million, growing 82.98% year-over-year. This demonstrates the company's platform is scaling rapidly, validating its core growth thesis in the high-potential AI healthcare market.
- Dramatic Gross Margin Expansion to 90%: Gross margin surged to 89.74% in Q4 2025 from 61.61% in Q3, indicating a powerful shift towards higher-margin software/data services. This structural improvement significantly enhances the path to future profitability.
- Analyst Consensus Bullish with High Conviction: Four covering analysts are unanimously bullish (3 Buys, 1 Neutral), reaffirming ratings in March 2026 despite the stock's 42% six-month decline. This suggests institutional belief in the long-term story remains intact.
- Valuation Multiple Compressed from Extreme Highs: The PS ratio has collapsed from a historical high of 51.8x to 8.09x, de-risking the stock from a speculative premium. The forward PEG of 0.61 suggests the market is pricing in very high future growth.
Bearish
- Severe Cash Burn & Negative Free Cash Flow: Trailing twelve-month free cash flow is -$404.0 million, with annual operating cash flow at -$218.1 million. This unsustainable burn rate necessitates future capital raises, risking shareholder dilution.
- Persistent Net Losses & Negative ROE: The company reported a Q4 net loss of $54.2 million and a deeply negative Return on Equity of -49.87%. Profitability remains elusive despite rapid revenue growth.
- Technical Downtrend & High Short Interest: The stock is down 41.59% over six months and trades just 10% above its 52-week low. A short ratio of 5.82 indicates intense negative sentiment and potential for further selling pressure.
- Leveraged Balance Sheet: A debt-to-equity ratio of 1.66 indicates significant financial leverage. This amplifies risk if revenue growth slows or interest expenses rise, increasing financial distress potential.
TEM Technical Analysis
The stock is in a pronounced downtrend, with a 1-year price change of -2.58% and a more severe 6-month decline of -41.59%, significantly underperforming the SPY's 30.59% gain over the same period. Currently trading at $52.12, the price sits near the lower end of its 52-week range ($41.73 to $104.32), indicating it is trading at approximately 10% above its 52-week low, which suggests the stock is deeply oversold but may also represent a falling knife scenario without a clear catalyst for reversal. Recent momentum shows a short-term bounce with a 1-month price change of +11.46%, sharply outperforming the SPY's +8.7% gain, indicating a potential oversold rally; however, the 3-month trend remains deeply negative at -20.21%, signaling the longer-term bearish pressure remains intact despite the recent rebound.
This recent positive 1-month momentum of +11.46% diverges from the prevailing 1-year downtrend, potentially signaling a technical relief rally or a bottoming attempt after the steep decline. The stock's relative strength versus the market is positive over one month (+2.76) but deeply negative over one year (-33.17), highlighting a stark short-term vs. long-term performance dichotomy. The price action from the data shows a sharp drop from highs above $90 in late October 2025 to lows near $42 in late March 2026, with the recent bounce to the $50-$56 range suggesting a consolidation phase.
Key technical levels are clearly defined, with immediate support at the 52-week low of $41.73 and major resistance at the 52-week high of $104.32. A sustained break below the $42 support could trigger further downside, while a move above the recent April high near $56.78 would be necessary to signal a more credible recovery attempt. With a short ratio of 5.82, the stock carries a high level of short interest, which could fuel a short-covering rally if positive catalysts emerge, but also indicates significant negative sentiment.
Beta
—
—
Max Drawdown
-59.0%
Largest decline past year
52-Week Range
$42-$104
Price range past year
Annual Return
-7.9%
Cumulative gain past year
| Period | TEM Return | S&P 500 |
|---|---|---|
| 1m | +18.1% | +12.6% |
| 3m | -21.2% | +2.5% |
| 6m | -44.3% | +4.3% |
| 1y | -7.9% | +28.4% |
| ytd | -19.8% | +4.3% |
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TEM Fundamental Analysis
Tempus AI is exhibiting explosive revenue growth, with Q4 2025 revenue of $367.2 million representing an 82.98% year-over-year increase. This follows sequential quarterly growth from $255.7 million in Q1 2025, demonstrating strong momentum. The company's primary investment thesis is predicated on this rapid scaling of its platform, though the sustainability of this growth rate is a key question as the base expands. With no segment data available, the growth appears broad-based across its data and diagnostic offerings.
The company remains unprofitable on a net income basis, reporting a Q4 2025 net loss of $54.2 million, which improved from a loss of $79.98 million in Q3 2025. However, gross margins are exceptionally high and improving, reaching 89.74% in the latest quarter, up from 61.61% in Q3 2025, indicating a favorable shift toward higher-margin services or software. The operating margin was -13.13% in Q4, a significant improvement from -17.94% in Q3, suggesting operating leverage is beginning to materialize as revenue scales.
The balance sheet shows a debt-to-equity ratio of 1.66, indicating a leveraged capital structure, but a strong current ratio of 3.13 provides ample short-term liquidity. A major concern is cash flow: the trailing twelve-month free cash flow is deeply negative at -$404.0 million, and operating cash flow for the full year 2025 was -$218.1 million. The company's return on equity is deeply negative at -49.87%, reflecting significant losses relative to shareholder equity. The business is currently consuming cash to fund its growth, relying on its IPO proceeds and debt to finance operations.
Quarterly Revenue
$367211000.0B
2025-12
Revenue YoY Growth
+0.82%
YoY Comparison
Gross Margin
+0.89%
Latest Quarter
Free Cash Flow
$-403985000.0B
Last 12 Months
Revenue & Net Income Trends (2 Years)
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Valuation Analysis: Is TEM Overvalued?
Given the company's negative net income and negative EBITDA, the primary valuation metric selected is the Price-to-Sales (PS) ratio. The trailing PS ratio is 8.09x, while the Enterprise Value-to-Sales (EV/Sales) is 7.68x. The forward-looking PEG ratio of 0.61, based on estimated earnings growth, suggests the market is pricing in very high future growth to justify the current sales multiple.
Comparable industry valuation multiples are not provided in the dataset, preventing a direct peer comparison. However, a PS ratio of approximately 8x for a healthcare technology company with over 80% revenue growth is typically at a premium to more mature healthcare IT peers but may be justified if the growth trajectory and path to profitability are deemed credible. The lack of profitability necessitates a growth-centric valuation framework.
Historically, the stock's own PS ratio has fluctuated dramatically, from a high of 51.8x in September 2024 to the current 8.09x as of the latest data. The current PS ratio is near the lower end of its own historical range, reflecting the significant compression in valuation multiple as the stock price has fallen sharply despite revenue growth. This suggests the market has de-risked the story, pricing in slower future growth or higher execution risk, moving from a premium 'story stock' multiple to a more grounded level.
PE
-42.0x
Latest Quarter
vs. Historical
Mid-Range
5-Year PE Range -105x~0x
vs. Industry Avg
N/A
Industry PE ~N/A*
EV/EBITDA
-47.2x
Enterprise Value Multiple
Investment Risk Disclosure
Financial & Operational Risks are acute, centered on cash sustainability. The company is burning cash at a rate of -$404M TTM, with operating cash flow of -$218.1M for the full year 2025. This burn is funding its 83% revenue growth, but with a debt-to-equity of 1.66, future financing could be dilutive or expensive. Furthermore, while gross margins improved to 90%, the net margin remains deeply negative at -19.3%, indicating operating expenses are still overwhelming top-line gains. The path to profitability is not yet visible in the income statement.
Market & Competitive Risks include extreme valuation compression from its historical highs, reflecting a market shift from rewarding 'story' to demanding financial discipline. The stock's 58.96% max drawdown and severe underperformance versus the SPY (-33.17% relative strength over one year) highlight its high-beta, growth-stock nature, making it vulnerable to sector rotations away from unprofitable tech. As a disruptor in oncology diagnostics, it faces intense competition from established labs and other AI startups, where any slowdown in its blistering growth rate could lead to further multiple derating.
Worst-Case Scenario involves a 'growth stall' coupled with a tightening capital market. If revenue growth decelerates sharply from 83% while cash burn remains elevated, the company could be forced to raise equity near its 52-week low of $41.73, causing severe dilution. A failure to demonstrate a credible path to positive operating cash flow in the next few quarters could trigger analyst downgrades and a short-selling spiral. In this adverse scenario, a realistic downside from the current $52.12 is a retest and break below the $41.73 low, representing a potential loss of -20% to -25%.

