Gilead Sciences is a biopharmaceutical company that develops and commercializes innovative medicines for life-threatening diseases.
Its identity is that of a global leader in virology, defined by its core expertise in antiviral therapies that have transformed treatment for HIV, hepatitis, and other infectious diseases.
Updated: February 19, 2026, 16:00 EST
Technical Analysis GILD shows remarkable bullish momentum, having surged over 26% in three months and trading near its 52-week high. While this reflects strong investor enthusiasm, the stock appears overbought and may face near-term consolidation. The low beta confirms these gains are driven by company-specific catalysts rather than broader market trends.
Fundamentals Revenue growth remains stable, but profitability has weakened significantly with net income declining quarter-over-quarter. The company maintains solid liquidity and manageable debt levels, though operational efficiency metrics like ROE and inventory turnover are modest. Overall, Gilead’s financial health is adequate but not exceptional.
Valuation & Risk Valuation sends mixed signals: the forward P/E is reasonable at 17.5, but the very high EV/EBITDA and negative PEG ratio suggest overvaluation and expected earnings declines. Risks are moderated by low volatility and lack of short interest, though sector-specific challenges like patent cliffs remain.
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While GILD’s recent rally and stable revenue base are positive, declining profitability and concerning valuation metrics offset its strengths. The stock appears priced for perfection, and the absence of strong earnings growth visibility limits upside potential. Investors may consider waiting for a pullback or clearer signs of operational improvement before establishing a position.
*Note: This is not investment advice, for reference only.*
Based on the provided analysis, here is a 12-month outlook for Gilead Sciences (GILD):
12-Month Outlook for GILD
The primary catalyst for GILD is the continued commercial execution and potential pipeline updates for its core virology portfolio, which drove the recent 26% surge; however, this positive momentum appears largely priced in. Key risks center on persistent declines in profitability and the concerning valuation signals from its negative PEG ratio, indicating expected earnings deterioration, alongside longer-term sector challenges like patent expirations. Given the stock's overbought condition and lack of clear earnings growth visibility, the near-term trajectory is likely range-bound to slightly negative, with a target price range gravitating towards the $140-$150 area as the market seeks a more attractive entry point aligned with its fundamental weaknesses.
Most Wall Street analysts are optimistic about Gilead Sciences, Inc.'s 12-month outlook, with consensus target around $151.12, indicating expected upside potential.
Overall, GILD has investment potential but also faces challenges. Here are key factors to weigh before investing.
GILD has demonstrated exceptional bullish momentum with substantial gains across multiple timeframes. The stock's strong positive performance significantly outpaces the market, driven by recent catalysts.
Over the past one and three months, GILD has surged over 26%, dramatically outperforming the broader market by more than 26 percentage points. This explosive short-term rally indicates extremely strong positive momentum, supported by a low beta that suggests these gains are not simply tracking market movements but are company-specific.
Currently trading at $155.27, GILD sits near its 52-week high of $157.29, placing it in the upper 99th percentile of its yearly range. The proximity to the all-time high, combined with the recent parabolic move, suggests the stock is in overbought territory and may be due for consolidation.
| Period | GILD Return | S&P 500 |
|---|---|---|
| 1m | +21.7% | +1.0% |
| 3m | +20.7% | +1.9% |
| 6m | +25.9% | +6.5% |
| 1y | +37.3% | +12.1% |
| ytd | +24.3% | +0.2% |
Revenue & Profitability Gilead's Q4 revenue increased to $7.93 billion from $7.77 billion in Q3, showing modest sequential growth. However, profitability metrics declined significantly with net income dropping to $2.18 billion (27.5% margin) from $3.05 billion (39.3% margin) in the prior quarter, primarily due to substantial other expenses impacting Q4 results. The sequential contraction in both operating and net margins indicates pressure on earnings quality despite revenue stability.
Financial Health The company maintains solid liquidity with current and quick ratios of 1.68 and 1.31 respectively, indicating adequate short-term financial flexibility. However, the absence of debt ratio data in the report limits comprehensive leverage analysis, though the interest coverage ratio of 11.6x suggests comfortable debt servicing capacity. The operating cycle of 433 days, driven by high inventory days outstanding, warrants monitoring for working capital efficiency.
Operational Efficiency Gilead demonstrates moderate operational efficiency with ROE of 9.7% and asset turnover of 0.13, reflecting typical capital intensity in pharmaceuticals. The inventory turnover of 0.24 suggests slower inventory movement, consistent with the industry's characteristics. The company's operational performance appears steady but not exceptional, with room for improvement in asset utilization metrics.
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Try Now & Get Tesla Stock RewardBased on Gilead's current multiples, the stock appears overvalued despite a reasonable forward P/E. While the forward P/E of 17.5 suggests moderate earnings-based valuation, this is heavily contradicted by an extremely high EV/EBITDA of 65.3 and a negative PEG ratio. The negative PEG ratio indicates that analysts expect declining earnings growth, which materially undermines the attractiveness of the P/E ratio and points to potential overvaluation.
Unfortunately, a peer comparison cannot be completed as the required industry average data is not available. Without benchmark data for biotechnology or pharmaceutical industry multiples, it is impossible to determine if Gilead's valuation metrics are high or low relative to its competitors. This analysis would be significantly strengthened by access to comparative industry data.
Volatility Risk: GILD exhibits significantly low beta at 0.387, indicating the stock is historically much less volatile than the broader market. While its 1-year maximum drawdown of -17.46% is moderate, the low beta suggests defensive characteristics and subdued volatility risk relative to market swings.
Other Risks: The absence of notable short interest signals minimal active bearish sentiment, suggesting investors are not aggressively betting on a price decline. However, as a large-cap pharmaceutical company, GILD still faces fundamental risks including pipeline setbacks, patent expirations, and regulatory challenges that could impact performance.
Neutral. Recent strong bullish momentum and positive catalysts are offset by declining profitability and potential overvaluation based on negative PEG ratio. The stock appears technically overbought near 52-week highs while facing regulatory and pricing pressures. Suitable for momentum investors comfortable with pharma sector risks, but less appealing for value-focused investors given current valuation concerns.
Based on the provided data, Gilead (GILD) stock currently appears overvalued. While its forward P/E of 17.5 is reasonable, it is heavily undermined by a negative PEG ratio (-0.61), which signals declining earnings growth expectations, and an extremely high EV/EBITDA of 65.3. Compared to its historical context, these metrics—particularly the negative PEG and high EV/EBITDA—point to a valuation that is not supported by its growth and profitability outlook, especially following the recent significant contraction in net income margins.
Based on the provided information, here are the key risks of holding Gilead Sciences (GILD), ordered by importance:
1. Pipeline and Patent Risk: The company faces the fundamental risk of pipeline setbacks for new drugs and patent expirations on existing blockbusters, which could severely impact future revenue streams. 2. Profitability and Earnings Quality Risk: Recent quarterly results show a significant sequential decline in net income and profit margins despite stable revenue, indicating pressure on earnings quality. 3. Operational Efficiency Risk: The company exhibits a very high operating cycle of 433 days and slow inventory turnover, reflecting potential inefficiencies in working capital management that could tie up capital.
Based on the provided analysis, here is a forecast for Gilead Sciences (GILD) through 2026:
Our base case target for 2026 is in the $145-$155 range, essentially expecting the stock to trade sideways, while a bull case of $165-$180 would depend on successful pipeline execution. Key growth drivers include the sustained performance of its core virology portfolio and successful commercial launches from its oncology pipeline. These forecasts assume the company can stabilize profitability declines and manage patent expiration headwinds without major setbacks. However, this outlook is highly uncertain, heavily dependent on clinical trial outcomes and competitive dynamics, which could lead to significant deviation from these targets.