LNTH

Lantheus Holdings, Inc

$101.19

+1.56%
Aug 3, 2026
Bobby Quantitative Model
Lantheus Holdings, Inc. is a radiopharmaceutical-focused company that develops and commercializes diagnostic and therapeutic products to help clinicians find, fight, and follow disease, primarily in oncology and cardiology. The company operates in the specialty pharmaceutical and diagnostic imaging industry, with a portfolio anchored by PYLARIFY (a PSMA-targeted PET imaging agent for prostate cancer) and DEFINITY (an ultrasound contrast agent). Lantheus is a market leader in radiopharmaceutical precision diagnostics, leveraging its expertise to expand into therapeutic radiopharmaceuticals. The current investor narrative centers on the commercial momentum of PYLARIFY, which is driving robust revenue growth, and the company's strategic partnerships to advance its pipeline in radiopharmaceutical therapies, positioning it as a key player in the rapidly evolving field of targeted radionuclide therapy.

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BobbyInvestment Opinion: Should I buy LNTH Today?

Rating: Buy. The thesis is that Lantheus is a profitable, cash-generative leader in radiopharmaceutical diagnostics with a reasonable valuation and strong analyst support, despite near-term growth deceleration. The consensus rating is 'Buy' with an average target of $112.75, implying 13.2% upside.

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LNTH 12-Month Price Forecast

The AI assessment leans bullish due to the company's strong profitability, reasonable valuation, and positive analyst sentiment, despite the near-term growth slowdown. The key risk is whether PYLARIFY can sustain its market position and drive growth. If revenue growth re-accelerates or pipeline milestones are met, the stock could outperform; conversely, a continued slowdown or competitive threat would warrant a downgrade to neutral.

Historical Price
Current Price $101.19
Average Target $106.19
High Target $129.00
Low Target $47.25

Wall Street consensus

Most Wall Street analysts maintain a constructive view on Lantheus Holdings, Inc's 12-month outlook, with a consensus price target around $112.75 and implied upside of +11.4% versus the current price.

Average Target

$112.75

0 analysts

Implied Upside

+11.4%

vs. current price

Analyst Count

covering this stock

Price Range

$98 - $129

Analyst target range

Lantheus is covered by 12 analysts, with a consensus recommendation of 'Buy' and a mean recommendation score of 1.62 (where 1 is Strong Buy and 5 is Sell). The average price target is $112.75, implying an upside of 13.2% from the current price of $99.64. The distribution of ratings is bullish, with no Sell ratings and a majority of Buy or Outperform ratings, as evidenced by recent actions from firms like B. Riley Securities, Citizens, Mizuho, and Truist Securities, all maintaining positive stances. The high target of $129.00 suggests that some analysts see significant upside potential, likely driven by expectations of PYLARIFY's continued market share gains and the successful development of therapeutic radiopharmaceuticals. The low target of $98.00 is slightly below the current price, indicating that even the most bearish analyst sees limited downside, which could be due to concerns about competition or regulatory risks. The relatively wide spread between the low and high targets (31.6% difference) reflects uncertainty about the company's future growth trajectory, but the overall sentiment remains positive, with no recent downgrades and several reaffirmations of Buy ratings in the past few months.

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Bulls vs Bears: LNTH Investment Factors

Lantheus presents a mixed picture: strong profitability, a leading product in PYLARIFY, and a reasonable valuation relative to peers, but offset by decelerating revenue growth and heavy reliance on a single product. The bull case is supported by analyst optimism and a solid balance sheet, while the bear case hinges on growth sustainability and competitive threats. Currently, the evidence slightly favors the bull side due to the attractive forward PE and strong cash flow, but the key tension is whether PYLARIFY can maintain its market share and drive growth, or if competition and market saturation will cap upside. The most critical factor to watch is the trajectory of PYLARIFY sales and any pipeline updates that could diversify revenue.

Bullish

  • Strong PYLARIFY momentum: Oncology segment (PYLARIFY) generated $240.9M in Q1 2026, flat YoY but still the primary growth driver. The product's market leadership in PSMA PET imaging supports continued adoption, and the company is expanding into therapeutic radiopharmaceuticals, which could unlock new revenue streams.
  • Attractive valuation vs. peers: Trailing PE of 19.2x is 12.6% below the industry average of 22x, and forward PE of 15.8x implies expected earnings growth of ~21.8%. This discount suggests the market is not fully pricing in the company's growth potential, especially given its strong profitability.
  • Strong profitability and cash flow: Gross margin is 61.2%, operating margin is 20.2%, and net margin is 15.2%. Free cash flow TTM is $371.7M, providing ample liquidity for R&D and strategic investments. ROE is 21.4%, indicating efficient use of shareholder capital.
  • Bullish analyst sentiment: Consensus rating is 'Buy' with a mean score of 1.62 (1=Strong Buy, 5=Sell). Average price target of $112.75 implies 13.2% upside, and the high target of $129 suggests 29.4% upside. No Sell ratings, with recent reaffirmations from multiple firms.

Bearish

  • Revenue growth deceleration: Q1 2026 revenue grew only 1.23% YoY, a sharp slowdown from prior double-digit growth. Revenue has plateaued around $377-407M over the last four quarters, suggesting market saturation or competitive pressures in the core diagnostic imaging business.
  • High valuation relative to growth: PEG ratio is -0.82, which is negative and indicates that the earnings growth rate is expected to be negative or the metric is distorted. This raises concerns about whether the forward PE of 15.8x is justified if growth does not materialize as expected.
  • Dependence on single product: PYLARIFY accounts for ~64% of total revenue ($240.9M out of $377.3M). This concentration risk means any competitive threat, regulatory setback, or reimbursement change could significantly impact the company's financials.
  • Recent price momentum overextension: Stock is trading at 89.1% of its 52-week range, near the high of $111.86. The 1-month return is -8.55%, indicating a recent pullback, and the stock has more than doubled from its 52-week low of $47.25, suggesting potential for profit-taking.

LNTH Technical Analysis

Lantheus has been in a strong uptrend over the past year, with the stock price rising 39.96% over the trailing twelve months. As of July 31, 2026, the stock trades at $99.64, which is 89.1% of its 52-week range (low of $47.25, high of $111.86), indicating it is near the upper end of its range. This positioning suggests strong momentum, but also potential overextension, as the stock has rallied significantly from its lows. The 52-week low was set in the past year, and the stock has more than doubled from that level, reflecting a robust recovery and sustained investor optimism.

Beta

-0.03

-0.03x market volatility

Max Drawdown

-40.2%

Largest decline past year

52-Week Range

$47-$112

Price range past year

Annual Return

+43.4%

Cumulative gain past year

PeriodLNTH ReturnS&P 500
1m-7.9%+1.7%
3m+17.9%+4.7%
6m+53.5%+10.4%
1y+43.4%+21.9%
ytd+50.4%+11.1%

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LNTH Fundamental Analysis

Lantheus reported revenue of $377.3 million in Q1 2026, representing a modest 1.23% year-over-year growth, which is a slowdown from the double-digit growth rates seen in prior quarters. The company's revenue has been relatively flat over the last four quarters, with Q4 2025 revenue of $406.8 million and Q3 2025 revenue of $384.0 million, indicating a plateau. However, the product mix is shifting, with Oncology (PYLARIFY) contributing $240.9 million in Q1 2026, up from $240.9 million in Q1 2025, while Cardiology (DEFINITY) declined to $84.6 million from $84.6 million, showing a stable but not growing core business. The revenue growth is being driven by PYLARIFY's continued adoption, but the overall growth rate has decelerated, which may raise concerns about market saturation or competitive pressures.

Quarterly Revenue

$377333000.0B

2026-03

Revenue YoY Growth

+1.2%

YoY Comparison

Gross Margin

61.2%

Latest Quarter

Free Cash Flow

$371695000.0B

Last 12 Months

Revenue & Net Income Trends (2 Years)

Revenue Breakdown

Cardiology
DEFINITY
License and Royalty Revenues
Oncology
PYLARIFY
Product
Strategic Partnerships And Other

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Valuation Analysis: Is LNTH Overvalued?

Given that Lantheus is profitable, the primary valuation metric selected is the price-to-earnings (PE) ratio. The trailing PE is 19.23x, while the forward PE is 15.79x, indicating that the market expects earnings growth of approximately 21.8% over the next year. This forward discount suggests that analysts anticipate continued earnings expansion, likely driven by PYLARIFY's growth and margin improvements. The PEG ratio is negative at -0.82, which is unusual and may indicate that the earnings growth rate is expected to be negative or that the metric is not meaningful due to non-recurring items. Compared to the industry average PE of 22x (based on specialty pharmaceutical peers), Lantheus trades at a 12.6% discount, which could be justified by its lower growth rate relative to some peers or by concerns about the sustainability of PYLARIFY's growth. Historically, Lantheus's PE has ranged from 7.9x to 31.3x over the past two years, with the current trailing PE of 19.2x sitting near the middle of that range, suggesting that the stock is fairly valued relative to its own history.

PE

19.2x

Latest Quarter

vs. Historical

Mid-Range

5-Year PE Range 8x~31x

vs. Industry Avg

N/A

Industry PE ~N/A*

EV/EBITDA

11.8x

Enterprise Value Multiple

Investment Risk Disclosure

Financial risks include the deceleration in revenue growth, which fell to 1.23% YoY in Q1 2026, and the plateau in quarterly revenue around $377-407M. This could pressure margins if fixed costs remain high, though current operating margin of 20.2% is healthy. The company carries a debt-to-equity ratio of 0.57, which is manageable, but any increase in debt to fund pipeline development could raise financial risk. Additionally, the negative PEG ratio (-0.82) suggests potential earnings volatility, and the payout ratio of 0% means no dividend cushion for investors.