LNTH

Lantheus Holdings, Inc

$102.82

-6.43%
Jul 6, 2026
Bobby Quantitative Model
Lantheus Holdings, Inc. is a radiopharmaceutical-focused company that develops, manufactures, and commercializes diagnostic and therapeutic agents to help clinicians find, fight, and follow diseases, primarily cancer. It operates within the specialty pharmaceutical industry, with a portfolio segmented into Radiopharmaceutical Oncology, Precision Diagnostics, and Strategic Partnerships. The company has established itself as a key player in the targeted radiopharmaceutical space, driven by the commercial success of its prostate cancer imaging agent, PYLARIFY. The current investor narrative centers on the company's transition to a profitable growth story, fueled by robust sales of its flagship products and its strategic positioning within the expanding field of precision oncology diagnostics and therapeutics.

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LNTH 12-Month Price Forecast

Historical Price
Current Price $102.82
Average Target $102.82
High Target $118.24299999999998
Low Target $87.39699999999999

Wall Street consensus

Most Wall Street analysts maintain a constructive view on Lantheus Holdings, Inc's 12-month outlook, with a consensus price target around $133.67 and implied upside of +30.0% versus the current price.

Average Target

$133.67

7 analysts

Implied Upside

+30.0%

vs. current price

Analyst Count

7

covering this stock

Price Range

$82 - $134

Analyst target range

Buy
2 (29%)
Hold
3 (43%)
Sell
2 (29%)

Analyst coverage for LNTH is limited, with data indicating only 7 analysts providing estimates. The consensus recommendation and average price target are not explicitly provided in the dataset. The estimated EPS range for the covered period is $8.17 to $9.70, with an average of $8.60, and the estimated revenue range is $2.11 billion to $2.41 billion, averaging $2.19 billion. Without a consensus price target, the implied upside or downside from the current price cannot be calculated, indicating a lack of clear directional consensus from the sell-side. The institutional ratings data shows recent activity but mixed signals. In March 2026, Truist Securities maintained a Buy rating, while Jones Trading downgraded from Buy to Hold. Earlier in February 2026, firms like Mizuho and Citizens reiterated Outperform ratings. This pattern of mostly reiterated bullish ratings alongside a notable downgrade suggests underlying optimism is being tempered by valuation concerns after the stock's significant run-up. The limited number of covering analysts and the recent downgrade highlight that while institutional interest exists, conviction may be wavering at current price levels, contributing to higher uncertainty.

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LNTH Technical Analysis

The stock is in a powerful, sustained uptrend, evidenced by a 1-year price change of +35.33% and a 6-month surge of +63.41%. As of the latest close at $109.01, LNTH is trading at the very top of its 52-week range, just $0.01 below its 52-week high of $109.02, indicating strong momentum but also potential overextension and vulnerability to profit-taking. Recent momentum has been exceptionally strong, with the stock up 8.94% over the past month and 46.38% over the past three months, significantly outpacing the SPY's returns of -2.17% and +15.8%, respectively, over the same periods. This acceleration suggests the uptrend is gaining strength, though the proximity to all-time highs warrants caution for new entries. Key technical support is anchored at the 52-week low of $47.25, while immediate resistance is the 52-week high of $109.02. A confirmed breakout above $109.02 could signal a continuation of the bullish trend, whereas a rejection at this level may lead to a consolidation or pullback. The stock exhibits low correlation with the broader market, as indicated by a beta of -0.043, meaning its price movements are largely independent of market swings. However, the high short ratio of 4.75 suggests a significant bearish sentiment among short sellers, which could fuel a short squeeze if positive momentum continues, adding to volatility.

Beta

-0.06

-0.06x market volatility

Max Drawdown

-40.2%

Largest decline past year

52-Week Range

$47-$112

Price range past year

Annual Return

+27.9%

Cumulative gain past year

PeriodLNTH ReturnS&P 500
1m+1.8%+1.9%
3m+31.7%+14.0%
6m+48.2%+8.9%
1y+27.9%+20.1%
ytd+52.8%+10.2%

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LNTH Fundamental Analysis

Revenue growth has been positive but shows signs of deceleration on a quarterly basis. The most recent Q4 2025 revenue was $406.79 million, representing a year-over-year growth of 4.01%. However, this growth rate is modest compared to the explosive performance seen in prior quarters, such as Q3 2024 which had revenue of $378.73 million. Segment data reveals the Radiopharmaceutical Oncology line, driven by PYLARIFY ($240.2 million in the period), is the primary growth driver, while Precision Diagnostics, including DEFINITY ($85.3 million), contributes a stable revenue base. The company is solidly profitable, with Q4 2025 net income of $54.09 million and a net margin of 13.3%. Gross margin remains healthy at 59.21% for the quarter, consistent with the company's full-year gross margin of 61.10%. This demonstrates the company's ability to maintain strong pricing power and cost control within its specialized pharmaceutical business, supporting a transition to sustainable earnings. Balance sheet health is robust, characterized by a strong liquidity position. The current ratio is 2.70, indicating ample short-term assets to cover liabilities. The debt-to-equity ratio is a manageable 0.57, reflecting a conservative capital structure. Most notably, the company generates substantial cash, with trailing twelve-month free cash flow of $348.64 million and a return on equity of 21.43%, signaling efficient use of shareholder capital and the ability to self-fund growth initiatives and potential share repurchases.

Quarterly Revenue

$406786000.0B

2025-12

Revenue YoY Growth

+0.04%

YoY Comparison

Gross Margin

+0.59%

Latest Quarter

Free Cash Flow

$348639000.0B

Last 12 Months

Revenue & Net Income Trends (2 Years)

Revenue Breakdown

DEFINITY
License and Royalty Revenues
Other Precision Diagnostics
PYLARIFY
Product
Radiopharmaceutical Oncology
Strategic Partnerships And Other
Techne Lite
Total Precision Diagnostics

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Valuation Analysis: Is LNTH Overvalued?

Given the positive net income, the primary valuation metric is the Price-to-Earnings (PE) ratio. The trailing PE ratio is 19.23x, while the forward PE is lower at 17.04x. This gap suggests the market anticipates earnings growth, as the forward multiple prices in higher future profits, aligning with analyst EPS estimates averaging $8.60. Compared to industry averages, specific data is not available in the provided dataset for a direct sector PE comparison. Therefore, a peer comparison cannot be quantified. However, a trailing PE of ~19x for a healthcare company with over 20% ROE and strong cash flow generation could be considered reasonable, especially if growth expectations are met. Historically, LNTH's valuation has fluctuated significantly. The current trailing PE of 19.23x sits well below its recent historical highs, such as the 31.04x seen in Q3 2025 and far below the extreme levels above 100x from periods of minimal earnings. This suggests the stock is not at peak historical valuation multiples, potentially leaving room for expansion if growth continues, though it is above the deeply negative multiples from its loss-making phases.

PE

19.2x

Latest Quarter

vs. Historical

High-End

5-Year PE Range -498x~40x

vs. Industry Avg

N/A

Industry PE ~N/A*

EV/EBITDA

11.8x

Enterprise Value Multiple