ONC

ONC

Onc is a pharmaceutical company focused on developing innovative treatments for cancer.
The company specializes in creating targeted therapies within the oncology sector. Onc positions itself as a dedicated oncology firm with a pipeline of novel drug candidates aimed at addressing significant unmet medical needs in cancer care.

$346.75 -4.31 (-1.23%)

Updated: January 14, 2026, 16:00 EST

Analyzed by Rockflow Bobby Quantitative Model โœ“ Updated Daily

Investment Opinion: Should I buy ONC Today?

Based on the comprehensive analysis of ONC, I recommend a cautious approach with a neutral-to-sell bias. The stock is not recommended for purchase at current levels.

Technical Analysis shows strong momentum with the stock approaching its 52-week high, suggesting it may be overbought despite positive trends. Fundamentals reveal a company with excellent profitability and a rock-solid balance sheet, but operational efficiency metrics like asset turnover are weak. Most critically, Valuation presents extreme risk, with PE ratios above 100 and a negative PEG ratio indicating the stock price is disconnected from its earnings growth potential.

While the companyโ€™s financial health is robust, the current share price already reflects extremely optimistic future growth. The combination of premium valuation and operational inefficiencies creates significant downside risk, making it difficult to justify a new investment. Investors might consider waiting for a more attractive entry point or clearer signs of improved operational execution.

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ONC 12-Month Price Forecast

RockFlow Model Forecast: Three Scenarios for 2026

Based on the provided analysis, here is a 12-month outlook for ONC:

Key Catalysts: Positive momentum could continue if the company can translate its excellent profitability and strong balance sheet into improved operational execution and higher asset turnover. Any announcements of strategic initiatives to address these inefficiencies would be a major positive catalyst.

Potential Risks: The primary risk is a significant correction due to its extreme valuation multiples (PE >100), suggesting the stock is overbought and priced for perfection. The negative PEG ratio indicates the current price is not supported by its earnings growth potential, creating high vulnerability to any negative earnings surprises or a broader market shift away from premium-priced stocks.

Outlook: The outlook is cautious. While the company's financial health provides a floor, the astronomical valuation presents substantial downside risk. The analyst's neutral-to-sell bias suggests the stock is more likely to underperform or correct toward a more reasonable valuation over the next 12 months than it is to sustain its current levels. A price target is not provided, but a move significantly below the current $351 level would be expected to better reflect the company's operational challenges.

Wall Street Consensus

Most Wall Street analysts are optimistic about ONC's 12-month outlook, with consensus target around $346.75, indicating expected upside potential.

Average Target
$346.75
27 analysts
Implied Upside
+0%
vs. current price
Analyst Count
27
covering this stock
Price Range
$277 - $451
Analyst target range
Buy Buy
25 (93%)
Hold Hold
1 (4%)
Sell Sell
1 (4%)

Bulls vs Bears: ONC Investment Factors

Overall, ONC has investment potential but also faces challenges. Here are key factors to weigh before investing.

Bullish Bullish
  • Strong Earnings Performance: Recent earnings beat expectations, suggesting a solid financial foundation.
  • Upgraded Relative Strength Rating: RS Rating improved to 92, indicating strong market momentum.
  • Sustained Stock Price Surge: Stock is up 9% today with a 91% one-year gain.
  • High Investor Confidence: Strong institutional momentum noted in Q3 2025 investor letters.
  • Increased Market Visibility: Participation in J.P. Morgan conference boosts investor awareness.
Bearish Bearish
  • Subdued Price Reaction to Earnings: Strong earnings did not significantly lift the stock price.
  • CEO Stock Sale: CEO John Oyler sold 75,631 shares, potentially signaling concerns.
  • COO Stock Sale: President and COO sold $1.52 million in stock, raising red flags.
  • High Valuation Concerns: 91% surge may have priced in expectations, limiting upside.
  • Potential Overbought Conditions: Rapid price increase could lead to a near-term correction.
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ONC Technical Analysis

Overall Assessment ONC has demonstrated strong intermediate-term performance with moderate volatility, posting a solid 4.54% gain over the last three months while outperforming the market.

Short-term Performance The stock's recent momentum is notably strong, evidenced by a significant 9.42% surge over the past month. This short-term performance, coupled with a positive 3-month relative strength of 1.17% against the market, indicates the stock is in a clear uptrend and gaining bullish momentum.

Current Position Trading at $351.06, ONC is positioned in the upper-middle portion of its 52-week range ($191.50 to $385.22), approximately 74% above its low. While the price is not at an extreme high, its proximity to the 52-week peak and substantial recent advance suggest it may be approaching overbought territory, warranting caution for new entries despite the positive momentum.

๐Ÿ“Š Beta
0.47
0.47x market volatility
๐Ÿ“‰ Max Drawdown
-25.9%
Largest decline past year
๐Ÿ“ˆ 52-Week Range
$196-$385
Price range past year
๐Ÿ’น Annual Return
+71.9%
Cumulative gain past year
Period ONC Return S&P 500
1m +8.7% +1.3%
3m +8.3% +5.7%
6m +35.6% +10.6%
1y +71.9% +16.5%
ytd +11.5% +1.1%

ONC Fundamental Analysis

Revenue & Profitability ONC demonstrated solid revenue growth, increasing from $1.315 billion in Q2 to $1.412 billion in Q3. The company maintains strong gross profit margins above 86%, reflecting excellent pricing power and cost management. Net income also improved significantly, rising from $94.3 million to $124.8 million quarter-over-quarter, though the net profit margin of 8.8% remains modest relative to the gross margin due to substantial R&D investments.

Financial Health The company exhibits exceptional liquidity with current and quick ratios well above 2.0, supported by a cash ratio of 1.70. With a low debt ratio of just 13.4% and minimal long-term debt, ONC maintains a conservative capital structure. The cash conversion cycle of 123 days suggests some capital tied up in operations, but the strong cash position provides ample financial flexibility.

Operational Efficiency Operational metrics show mixed performance with an asset turnover of 0.19 indicating relatively low revenue generation from the asset base. However, return on equity improved to 3.0% in Q3 from lower levels in previous quarters. The high days inventory outstanding of 244 days suggests potential inventory management challenges, though this may be industry-specific for a biotechnology company.

Quarterly Revenue
$1.4B
2025-09
Revenue YoY Growth
N/A
YoY Comparison
Gross Margin
86.1%
Latest Quarter
Free Cash Flow
$0.5B
Last 12 Months

Revenue & Net Income Trends (2 Years)

Revenue Breakdown

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Valuation Analysis: Is ONC Overvalued?

Valuation Level Analysis

ONC's valuation metrics present significant concerns. Its trailing PE of 167.67 and forward PE of 123.66 are exceptionally high, indicating the market prices substantial future growth expectations despite negative fundamentals. The PB ratio of 8.95 and PS ratio of 9.61 further suggest premium pricing relative to the company's book value and sales. Most alarming is the negative PEG ratio of -1.49, which signals deteriorating earnings growth prospects, while the extremely high EV/EBITDA of 360 suggests minimal current earnings power relative to enterprise value.

Peer Comparison Analysis

Without specific industry average data provided, ONC's valuation appears dramatically elevated against typical market standards. The PS ratio near 10 significantly exceeds reasonable levels for most industries, suggesting extreme overvaluation unless accompanied by extraordinary growth rates. The negative PEG ratio contradicts the high multiples, creating a fundamental disconnect that typically indicates severe overvaluation regardless of sector comparisons. These metrics collectively point to substantial valuation risk.

Current PE
176.2x
Latest Quarter
vs. Historical
Mid-Range
5-Year PE Range -4ร—-720ร—
vs. Industry Avg
N/A
Industry PE ~N/Aร—
EV/EBITDA
360.1x
Enterprise Value Multiple

Investment Risk Disclosure

Volatility Risk

ONC exhibits relatively low volatility risk with a beta of 0.471, indicating the stock is less volatile than the broader market. However, a maximum drawdown of -25.89% over the past year suggests investors have experienced significant peak-to-trough declines, highlighting potential downside risk despite the low beta.

Other Risks

The absence of notable short interest implies market sentiment is not significantly bearish, but this also warrants caution as it may indicate lower liquidity or analyst coverage. This lack of trading activity could pose liquidity risks, making larger transactions more challenging without impacting the stock's price.

FAQs

Is ONC a good stock to buy?

Neutral to cautious - While ONC shows strong operational momentum with solid earnings growth and bullish analyst sentiment, the extreme valuation metrics (P/E >160) create significant risk. Recent insider stock sales also temper enthusiasm despite the strong price surge. Suitable only for aggressive, growth-oriented investors comfortable with high volatility and valuation risk.

Is ONC stock overvalued or undervalued?

Based on the valuation metrics provided, ONC stock appears significantly overvalued.

Key Valuation Metrics: * PE Ratio: 167.67 (extremely high) * PEG Ratio: -1.49 (negative, indicating deteriorating earnings growth) * PS Ratio: 9.61 (very high, suggesting premium pricing)

Comparison and Reasoning: The valuation multiples are exceptionally elevated compared to reasonable historical or industry standards. A PE ratio over 160 implies astronomical growth expectations that are not supported by the negative PEG ratio, which signals a fundamental disconnect. The high Price-to-Sales ratio further confirms the stock is priced at a significant premium. While the company shows solid revenue growth and a strong financial position, these positive fundamentals are far outweighed by the extreme valuation metrics, pointing to a high risk of overvaluation.

What are the main risks of holding ONC?

Based on the provided information, the key risks of holding ONC are:

1. Valuation and Momentum Risk: The stock is trading near its 52-week high after a significant recent advance, increasing its vulnerability to a price correction or profit-taking. 2. Operational Execution Risk: An extremely high days inventory outstanding (244 days) indicates potential challenges in inventory management or product demand, which could pressure future profitability. 3. Market Liquidity Risk: The noted absence of significant short interest and trading activity suggests lower liquidity, posing a risk for investors needing to execute large trades without adversely impacting the stock price. 4. Industry-Specific Risk: As a biotechnology company with high R&D expenses (evident from the gap between gross and net margins), ONC faces inherent risks related to clinical trial outcomes, regulatory approvals, and lengthy product development cycles.

What is the price forecast for ONC in 2026?

Based on the provided analysis, my forecast for ONC stock through 2026 is highly speculative due to its extreme valuation and operational inefficiencies.

* Target Price & Growth Drivers: A plausible base case sees the stock correcting to a range of $150-$250 as its valuation normalizes, while a bull case (~$400+) would require successfully leveraging its strong balance sheet to dramatically improve asset turnover and inventory management. * Assumptions & Uncertainty: This assumes the company addresses its operational challenges without major earnings disappointments. The forecast carries extreme uncertainty; the stock's performance is less tied to fundamentals and more to market sentiment towards its high-growth narrative, making it highly vulnerable to a sharp de-rating.