PFE

PFE

Pfizer is a global pharmaceutical company operating in the drug manufacturing industry.
Its core identity is that of a research-driven leader, distinguished by its extensive portfolio of medicines and vaccines.

$25.09 +0.06 (+0.24%)

Updated: December 28, 2025, 16:00 EST

Analyzed by Rockflow Bobby Quantitative Model ✓ Updated Daily

Investment Opinion: Should I buy PFE Today?

Analysis of Pfizer (PFE)

Technical Analysis PFE shows relative stability with modest quarterly gains, though it remains below its annual highs. Trading in the upper-middle of its 52-week range and exhibiting low volatility (beta of 0.42), the stock presents a technically neutral profile without clear overbought or oversold signals.

Fundamentals Pfizer displays solid revenue growth and strong gross profitability, supported by healthy margins and consistent operating income. However, operational efficiency remains a concern, with low asset turnover and an extended cash conversion cycle indicating working capital challenges. The conservative debt structure and adequate liquidity underscore financial stability.

Valuation & Peer Comparison Valuation metrics suggest moderate attractiveness, with a forward P/E of 8.3 hinting at potential undervaluation relative to earnings growth prospects. While precise peer data is unavailable, PFE’s multiples appear reasonable for a large-cap pharmaceutical firm, possibly trading at a sector discount.

Risk Assessment PFE’s low beta and contained drawdown history point to below-average volatility risk. However, company-specific risks such as patent cliffs or pipeline delays persist, though modest short interest reflects limited bearish sentiment.

Investment Recommendation Pfizer represents a balanced opportunity with stable fundamentals, reasonable valuation, and lower volatility. While operational inefficiencies are a concern, the stock’s defensive qualities and earnings potential support a cautious buy. Investors may consider PFE for steady exposure to the pharmaceutical sector, particularly given its discounted forward multiples.

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PFE 12-Month Price Forecast

RockFlow Model Forecast: Three Scenarios for 2026

Based on a comprehensive analysis, here is the 12-month outlook for Pfizer (PFE):

Pfizer's primary catalysts over the next year will be the successful launch and uptake of its newer non-COVID products, such as the Abrysvo vaccine and the acquired Seagen oncology portfolio, which are critical to offsetting the steep decline in COVID-related revenues. However, significant risks remain, including persistent revenue erosion from key drug patent expirations (loss of exclusivity) and the ongoing challenge of replacing the massive, albeit fading, COVID product sales. Given its defensive profile, reasonable valuation, and analyst sentiment, the stock appears positioned for moderate upside, with a target price range aligning with the analyst consensus around $28 - $29.

Wall Street Consensus

Most Wall Street analysts are optimistic about PFE's 12-month outlook, with consensus target around $28.62, indicating expected upside potential.

Average Target
$28.62
24 analysts
Implied Upside
+14%
vs. current price
Analyst Count
24
covering this stock
Price Range
$23 - $36
Analyst target range
Buy Buy
19 (79%)
Hold Hold
3 (12%)
Sell Sell
2 (8%)

Bulls vs Bears: PFE Investment Factors

Overall, PFE has investment potential but also faces challenges. Here are key factors to weigh before investing.

Bullish Bullish
  • Political Agreement Benefit: Pfizer's deal with Trump removes uncertainty for the entire pharmaceutical sector.
  • Positive After-Hours Movement: Stock showed strength with a rise in the Christmas Eve after-hours session.
  • Acquisition-Driven Growth: Recent acquisitions are part of a strategy to fuel future revenue streams.
Bearish Bearish
  • Weak Financial Guidance: Company lowered its 2026 earnings and revenue forecasts, missing Wall Street expectations.
  • Stock Underperformance: Pfizer's stock price has recently declined, trailing the broader S&P 500 index.
  • Post-Acquisition Integration Risk: Integrating recent acquisitions poses execution risks and potential for value erosion.
  • Market Share Threats: The company faces significant competitive pressures and threats to its product portfolio.
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PFE Technical Analysis

PFE has demonstrated relative stability with modest gains over the recent quarter, though it remains well below its annual highs after a significant drawdown.

The stock has seen a slight decline of 0.75% over the past month, but has gained 5.56% over the last three months, modestly outperforming the broader market by 1.16% during that period. Its low beta of 0.42 indicates significantly lower volatility compared to the overall market.

Currently trading at $25.03, PFE is positioned in the upper-middle portion of its 52-week range ($20.92 - $27.69), approximately 45% above its low. Following a 19.77% maximum drawdown, the stock appears to be in a relatively neutral position, showing neither strong overbought nor oversold conditions.

📊 Beta
0.42
0.42x market volatility
📉 Max Drawdown
-19.8%
Largest decline past year
📈 52-Week Range
$21-$28
Price range past year
💹 Annual Return
+1.1%
Cumulative gain past year
Period PFE Return S&P 500
1m -2.5% +2.6%
3m +6.0% +4.7%
6m +8.3% +16.8%
1y +1.1% +17.4%
ytd +1.1% +19.5%

PFE Fundamental Analysis

Revenue & Profitability Pfizer demonstrated strong revenue growth, increasing from $14.65 billion in Q2 to $16.65 billion in Q3 2025, while maintaining stable operating margins around 21-24%. The company shows robust gross profitability with a 74.9% gross margin in Q3, though net income margin improved slightly to 21.3% from 19.9% in the prior quarter. Operating income remained consistent at approximately $3.6 billion despite the revenue increase.

Financial Health Pfizer maintains a conservative debt structure with a debt-to-equity ratio of 0.665 and a moderate debt ratio of 29.6%. The interest coverage ratio of 5.4x indicates sufficient earnings to service debt obligations, though the cash flow to debt ratio of 0.075 suggests limited free cash flow relative to total debt. The current ratio of 1.28 indicates adequate short-term liquidity.

Operational Efficiency Operational metrics show challenges with a low return on equity of 3.8% and asset turnover of just 0.08, indicating inefficient asset utilization. The extended cash conversion cycle of 216 days reflects working capital inefficiencies, driven by high days inventory outstanding of 247 days. However, the company maintains strong operating cash flow conversion with an operating cash flow to sales ratio of 27.6%.

Quarterly Revenue
$16.7B
2025-09
Revenue YoY Growth
-5.9%
YoY Comparison
Gross Margin
75.0%
Latest Quarter
Free Cash Flow
$10.4B
Last 12 Months

Revenue & Net Income Trends (2 Years)

Revenue Breakdown

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Valuation Analysis: Is PFE Overvalued?

Valuation Level: Pfizer's valuation appears moderately attractive based on current multiples. The trailing PE of 14.6 and forward PE of 8.3 suggest earnings growth expectations, while the PB of 1.53 and PS of 2.27 are reasonable for a pharmaceutical company. The EV/EBITDA of 7.75 indicates solid operational efficiency and suggests the stock may be fairly valued to slightly undervalued relative to its current financial performance.

Peer Comparison: Without specific industry average data, a precise peer comparison cannot be conducted. However, given the pharmaceutical sector's typical valuation ranges, Pfizer's multiples appear to be in line with large-cap pharmaceutical peers. The forward PE ratio below 10 suggests Pfizer may be trading at a discount to many industry competitors, though this assessment requires actual industry benchmarks for confirmation.

Current PE
14.6x
Latest Quarter
vs. Historical
Mid-Range
5-Year PE Range -20×-1666×
vs. Industry Avg
-41.0%
Industry PE ~24.7×
EV/EBITDA
7.8x
Enterprise Value Multiple

Investment Risk Disclosure

Volatility risk for PFE appears moderately low compared to the broader market, as indicated by its Beta of 0.42, suggesting the stock is less volatile. The 1-year maximum drawdown of -19.77% shows a relatively contained historical downside, indicating a moderate level of volatility risk that is below average for the sector but still presents a notable drawdown potential for investors.

Other risks include a modest short interest of 2.75%, which implies limited bearish sentiment and low risk of a short squeeze. However, the stock may still face headwinds from company-specific factors such as patent expirations or pipeline setbacks, which are not fully captured by these quantitative metrics.

FAQs

Is PFE a good stock to buy?

Neutral outlook on PFE. While valuation appears reasonable with a forward PE of 8.3 and political developments provide stability, weak 2026 guidance and operational inefficiencies (3.8% ROE) create near-term headwinds. Suitable for long-term dividend investors seeking pharmaceutical exposure with patience for acquisition integration.

Is PFE stock overvalued or undervalued?

Based on the provided data, PFE stock appears undervalued.

Key valuation metrics supporting this view include a low forward P/E of 8.3 and an EV/EBITDA of 7.75, which are attractive relative to typical pharmaceutical industry averages. The primary reason is that the market appears to be undervaluing Pfizer's future earnings potential, as indicated by the significant discount between its trailing and forward P/E ratios. Despite operational inefficiencies like low asset turnover, its strong profitability (21% net margins) and solid financial health suggest the current price does not fully reflect its financial strength.

What are the main risks of holding PFE?

Based on Pfizer's current profile, here are the key risks of holding PFE stock, ordered by importance:

1. Pipeline and Patent Cliff Risk: The company faces significant revenue uncertainty from patent expirations on key drugs and potential setbacks in its drug development pipeline, which are not fully captured by current strong financials. 2. Operational Inefficiency Risk: Extremely low asset utilization (asset turnover of 0.08) and a prolonged cash conversion cycle (216 days) indicate fundamental operational challenges that pressure profitability and return on equity (3.8%). 3. Post-Peak Revenue Normalization Risk: Following the surge in COVID-19 product sales, the company is exposed to volatility and a potential sustained decline as it navigates the cyclical downturn and works to replace this substantial revenue stream.

What is the price forecast for PFE in 2026?

Based on Pfizer's current trajectory and market dynamics, here is the strategic forecast for PFE stock through 2026:

The 2026 base case target price is $29-$32, anticipating steady progress in launching new products like the Seagen oncology portfolio to partially offset COVID revenue declines and patent expiries. A bull case of $34-$37 would require faster-than-expected uptake of these new drugs and successful pipeline catalysts demonstrating significant commercial potential. The forecast assumes that Pfizer can execute on its non-COVID growth strategy without major pipeline setbacks and that investor sentiment shifts from its current COVID-overhang discount toward valuing its diversified pipeline.

Key growth drivers include: 1) the successful commercial integration and growth of the Seagen oncology assets, 2) strong uptake of newer vaccines like Abrysvo, and 3) operational efficiency improvements to bolster margins. This outlook is highly dependent on the uncertain pace of new product revenue generation against the steep decline in legacy products, making the forecast sensitive to quarterly execution.