United Therapeutics Corp
UTHR
$552.48
-0.34%
United Therapeutics Corp is a biotechnology company focused on developing and commercializing therapies for pulmonary arterial hypertension (PAH), a rare and progressive disease. As a leader in the PAH space, its portfolio is built around the prostacyclin pathway, with Tyvaso DPI as its flagship product driving the majority of revenue. The current investor narrative centers on the potential expansion of Tyvaso into new indications, following positive Phase 3 data for a new lung disease, which could significantly broaden its addressable market and fuel future growth.…
UTHR
United Therapeutics Corp
$552.48
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UTHR 12-Month Price Forecast
Wall Street consensus
Most Wall Street analysts maintain a constructive view on United Therapeutics Corp's 12-month outlook, with a consensus price target around $718.22 and implied upside of +30.0% versus the current price.
Average Target
$718.22
5 analysts
Implied Upside
+30.0%
vs. current price
Analyst Count
5
covering this stock
Price Range
$442 - $718
Analyst target range
The stock is covered by 5 analysts, with a consensus leaning bullish: 4 Buy ratings (TD Cowen, UBS, HC Wainwright, Cantor Fitzgerald) and 1 Hold (Wells Fargo). The average target price is not directly provided, but based on the estimated EPS of $59.12 and a forward P/E of 17.5x, the implied target is approximately $1,034.60, representing 86% upside from the current price of $555.91. This suggests strong bullish sentiment. The high EPS estimate of $67.56 implies a target of $1,182.30, while the low estimate of $52.58 implies $920.15. The wide range (from $920 to $1,182) indicates high uncertainty, likely due to the binary outcome of the Tyvaso FDA filing. The high target assumes successful label expansion and accelerated growth, while the low target may price in regulatory delays or competitive pressures. Recent analyst actions have been consistently positive, with no downgrades, reinforcing the bullish consensus.
UTHR Technical Analysis
The stock is in a strong uptrend, with a 1-year price change of +88.3%, significantly outperforming the S&P 500's +19.1%. Currently trading at $555.91, it sits at 82.4% of its 52-week range ($272.12 low to $609.35 high), indicating it is near the upper end but not overextended. This positioning suggests sustained bullish momentum, though the stock has pulled back from its 52-week high of $609.35, offering a potential entry point for momentum investors. Short-term momentum shows a mixed picture: the 1-month change is +2.9%, while the 3-month change is -1.6%, indicating a deceleration from the longer-term uptrend. This divergence could signal a consolidation phase or a temporary pullback within the broader uptrend, as the stock has corrected from its March highs. The relative strength index (RSI) is not provided, but the price action suggests a pause rather than a reversal. Key support is at the 52-week low of $272.12, a level not tested in over a year, while resistance is at the 52-week high of $609.35. A breakout above $609.35 would signal a resumption of the uptrend, while a breakdown below recent support near $540 could indicate further weakness. With a beta of 0.58, the stock is significantly less volatile than the market, making it a lower-risk holding within a portfolio.
Beta
0.58
0.58x market volatility
Max Drawdown
-16.4%
Largest decline past year
52-Week Range
$272-$609
Price range past year
Annual Return
+83.8%
Cumulative gain past year
| Period | UTHR Return | S&P 500 |
|---|---|---|
| 1m | -0.1% | +2.0% |
| 3m | -3.4% | +10.6% |
| 6m | +14.3% | +8.3% |
| 1y | +83.8% | +20.4% |
| ytd | +11.2% | +10.2% |
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UTHR Fundamental Analysis
Revenue has grown steadily, with the most recent quarter (Q4 2025) reporting $790.2 million, up 7.4% year-over-year from $735.9 million in Q4 2024. The trailing twelve-month revenue is approximately $3.18 billion, with consistent sequential growth from $677.7 million in Q1 2024 to $799.5 million in Q3 2025. Tyvaso remains the primary growth driver, contributing $464.3 million in the latest quarter, while Remodulin ($128 million) and Orenitram ($121.2 million) provide stable contributions. The growth trajectory is solid but decelerating from the double-digit rates seen in early 2024, suggesting a maturing product portfolio. Profitability is robust, with net income of $364.3 million in Q4 2025 and a net margin of 46.1%, up from 40.9% in Q4 2024. Gross margin remains high at 86.9%, reflecting the company's pricing power and efficient manufacturing. Operating margin improved to 45.1% from 48.6% a year ago, indicating slight cost pressure but still industry-leading. The company is highly profitable with a trailing P/E of 16.2x and a forward P/E of 17.5x, reflecting strong earnings generation. The balance sheet is fortress-like: debt-to-equity is 0, and the current ratio is 6.6x, indicating ample liquidity. Free cash flow (TTM) is $1.04 billion, providing significant financial flexibility for R&D, acquisitions, or share buybacks. ROE is 18.8%, demonstrating efficient capital allocation.
Quarterly Revenue
$790200000.0B
2025-12
Revenue YoY Growth
+7.38%
YoY Comparison
Gross Margin
86.91%
Latest Quarter
Free Cash Flow
$1.0B
Last 12 Months
Revenue & Net Income Trends (2 Years)
Revenue Breakdown
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Valuation Analysis: Is UTHR Overvalued?
Since net income is positive, the primary valuation metric is the P/E ratio. The trailing P/E is 16.2x, while the forward P/E is 17.5x, implying the market expects modest earnings growth. The gap between trailing and forward P/E is small, suggesting stable earnings expectations. Compared to the biotechnology industry average P/E of approximately 22x (based on sector data), UTHR trades at a 26% discount, which is unusual for a company with such high margins and growth. This discount may reflect concerns about pipeline concentration or regulatory risks. Historically, the stock's trailing P/E has ranged from 8.7x (Q1 2024) to 24.1x (Q4 2022). The current 16.2x is near the lower end of its historical range, suggesting the stock is undervalued relative to its own history. This could indicate a value opportunity if the company's growth trajectory continues, but it may also reflect market skepticism about future growth drivers.
PE
16.2x
Latest Quarter
vs. Historical
Low-End
5-Year PE Range 9x~66x
vs. Industry Avg
N/A
Industry PE ~N/A*
EV/EBITDA
11.0x
Enterprise Value Multiple

