Halozyme Therapeutics
HALO
$69.50
-1.74%
Halozyme Therapeutics, Inc. is a biotechnology company focused on developing and commercializing novel oncology therapies, primarily through its proprietary ENHANZE drug delivery technology based on the rHuPH20 enzyme which facilitates the subcutaneous delivery of injected drugs. The company operates as a platform technology and product company, deriving significant revenue from collaborative licensing agreements with major biopharmaceutical partners, which allows its technology to be embedded in a growing portfolio of partnered biologic drugs. The current investor narrative is driven by the strong royalty-driven revenue growth from its partnered products, particularly the robust 51.6% year-over-year revenue growth in its most recent quarter, though this is juxtaposed against a significant quarterly net loss that has sparked debate about the sustainability of its profitability trajectory and the impact of its recent large acquisition.…
HALO
Halozyme Therapeutics
$69.50
HALO 12-Month Price Forecast
Wall Street consensus
Most Wall Street analysts maintain a constructive view on Halozyme Therapeutics's 12-month outlook, with a consensus price target around $90.35 and implied upside of +30.0% versus the current price.
Average Target
$90.35
2 analysts
Implied Upside
+30.0%
vs. current price
Analyst Count
2
covering this stock
Price Range
$56 - $90
Analyst target range
Analyst coverage for Halozyme appears limited, with data indicating only 2 analysts providing estimates, which suggests the stock may be under-followed relative to larger biotech peers, potentially leading to higher volatility and less efficient price discovery. The available data shows consensus estimates for EPS averaging $8.90 for the period, with a range from $8.56 to $9.16, and for revenue averaging $1.78 billion, ranging from $1.73B to $1.82B, indicating analysts have a relatively tight and bullish outlook on near-term financial performance. Institutional rating actions over the past several months show a stable, bullish bias among the firms that do cover it, with recent actions including reiterated 'Buy' or 'Overweight' ratings from Benchmark, TD Cowen, HC Wainwright, Citizens, and Morgan Stanley, while Wells Fargo and Goldman Sachs maintain 'Equal Weight' and 'Neutral' stances, respectively; the absence of recent downgrades signals underlying confidence in the business model despite the noisy quarterly earnings.
HALO Technical Analysis
The stock is in a clear, sustained long-term uptrend, with a 1-year price change of +32.96%, significantly outperforming the broader market's 27.04% gain. Currently trading at $71.6, the price sits at approximately 69% of its 52-week range ($51.06 to $82.22), indicating it has retreated meaningfully from its highs but remains well above its lows, suggesting a consolidation phase within a broader bullish trend. The stock has demonstrated strong relative strength over the past year with a 5.92% alpha versus the SPY, though it has underperformed recently with a negative 3-month relative strength of -6.32%. Short-term momentum shows signs of recovery, with the stock up 8.70% over the past month, which contrasts with a more modest 6.28% gain over the past three months; this 1-month acceleration suggests a potential resurgence in bullish sentiment after a period of consolidation and pullback from the February highs near $81. Key technical support is anchored at the 52-week low of $51.06, while immediate overhead resistance is at the 52-week high of $82.22; a decisive breakout above $82.22 would signal a resumption of the primary uptrend, while a break below the $70 support zone could indicate a deeper correction. The stock exhibits a beta of 0.884, indicating it is slightly less volatile than the broader market, which is notable for a biotech firm and may reflect its more stable, royalty-based revenue model.
Beta
0.87
0.87x market volatility
Max Drawdown
-29.3%
Largest decline past year
52-Week Range
$51-$82
Price range past year
Annual Return
+27.4%
Cumulative gain past year
| Period | HALO Return | S&P 500 |
|---|---|---|
| 1m | -0.8% | -0.1% |
| 3m | +9.2% | +12.0% |
| 6m | +11.7% | +8.8% |
| 1y | +27.4% | +22.9% |
| ytd | -1.2% | +8.8% |
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HALO Fundamental Analysis
Halozyme's revenue trajectory is exceptionally strong, with Q4 2025 revenue of $451.8 million representing a 51.6% year-over-year growth rate, a significant acceleration from the $298.0 million reported in Q4 2024. This growth is primarily driven by its high-margin royalty segment, which contributed $494.0 million in the latest period, alongside collaborative agreements at $95.1 million and product sales of $42.9 million. The company's profitability is highly volatile on a quarterly basis, as evidenced by a net income of -$141.6 million in Q4 2025 despite a robust gross margin of 78.1% and an operating margin of 58.4%; this quarterly loss contrasts sharply with the profitable quarters preceding it (e.g., Q3 2025 net income of $175.2 million), largely due to a $355.2 million 'total other income expenses net' line item, likely related to its recent acquisition. On a trailing twelve-month basis, the company remains profitable with a net margin of 22.7% and an ROE of 6.49%, indicating it generates value for shareholders. The balance sheet and cash flow position is solid, with a strong current ratio of 4.66 and a manageable debt-to-equity ratio of 43.9%; critically, the company generated substantial free cash flow of $644.6 million (TTM), providing ample internal funding for growth and strategic initiatives, which is further supported by an ROA of 22.1% demonstrating efficient use of assets.
Quarterly Revenue
$451767000.0B
2025-12
Revenue YoY Growth
+0.51%
YoY Comparison
Gross Margin
+0.77%
Latest Quarter
Free Cash Flow
$644588000.0B
Last 12 Months
Revenue & Net Income Trends (2 Years)
Revenue Breakdown
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Valuation Analysis: Is HALO Overvalued?
Given the company's positive trailing twelve-month net income, the primary valuation metric selected is the Price-to-Earnings (P/E) ratio. Halozyme trades at a trailing P/E of 25.45x, which is substantially lower than its forward P/E of 7.24x, implying the market expects a dramatic surge in earnings over the next twelve months, likely tied to the full integration and contribution from its recent acquisition. Compared to the broader biotechnology industry, which often trades at high P/E multiples due to growth expectations, Halozyme's trailing multiple appears reasonable given its robust revenue growth and platform royalty model, though a direct industry average P/E is not provided in the data for precise comparison. Historically, the stock's own P/E ratio has been extremely volatile, ranging from deeply negative figures during loss-making quarters to over 50x in early 2021; the current trailing P/E of 25.45x is towards the lower end of its historical spectrum when profitable, suggesting the stock is not priced for extreme optimism and may offer value if the company can return to consistent quarterly profitability as anticipated by the low forward multiple.
PE
25.5x
Latest Quarter
vs. Historical
Mid-Range
5-Year PE Range -14x~67x
vs. Industry Avg
N/A
Industry PE ~N/A*
EV/EBITDA
11.1x
Enterprise Value Multiple

